⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855699 | 1.00 | — | — | |
| SCHEMBL21557 | 0.92 | EPHX1 (0.42) | — | |
| SCHEMBL30436843 | 0.90 | EPHX1 (0.46) | — | |
| SCHEMBL20840762 | 0.90 | EPHX1 (0.46) | — | |
| SCHEMBL13932787 | 0.90 | EPHX1 (0.46) | — | |
| SCHEMBL8332892 | 0.90 | EPHX1 (0.46) | — | |
| SCHEMBL117988 | 0.90 | EPHX1 (0.46) | — | |
| SCHEMBL10700618 | 0.90 | EPHX1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL28052855 | 0.90 | EPHX1 (0.40) | — | |
| SCHEMBL27325560 | 0.90 | EPHX1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491671-A | Process for the preparation of N-substituted imido-dicarboxylic acid diaryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | claimed |
| CN-117510500-A | Preparation method of asperazepanones alkaloid and application of asperazepanones alkaloid as anti-inflammatory drug | 中国海洋大学 | 2024-02-06 | — | — | CN | disclosed |
| EP-4289951-A2 | CIRCULAR RNA COMPOSITIONS AND METHODS | Orna Therapeutics, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-117050043-A | 3-phenyl dibenzofuran compound and preparation method and application thereof | 中国海洋大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-116726010-A | Application of macrolide derivative in preparation of medicines for inhibiting pro-inflammatory cytokine acting agents | 中国海洋大学 | 2023-09-12 | — | — | CN | disclosed |
| US-20230173024-A1 | FACTOR B INHIBITORS AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2023-06-08 | — | — | US | disclosed |
| CN-112851622-B | Macrolide brefeldin A ester derivative and application thereof | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112851622-A | Macrolide brefeldin A ester derivative and application thereof | 中国海洋大学 | 2021-05-28 | — | — | CN | disclosed |
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |
| US-10274824-B2 | Photobase generators and photoresist compositions comprising same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2019-04-30 | — | — | US | disclosed |
| US-20140057907-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2010027097-A1 | TRI-SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-03-11 | — | — | WO | disclosed |
| EP-2105146-A1 | Nucleic-acid triggered release of molecules | Riken (JP) | 2009-09-30 | — | — | EP | disclosed |
| EP-1670757-B1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1422260-B1 | Curable fluoropolyether rubber compositions and rubber articles | SHINETSU CHEMICAL CO (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-20080107608-A1 | 5-Substituted-2-Arylpyridines | GE PING | 2008-05-08 | — | — | US | disclosed |
| US-7329663-B2 | Substituted-triazolopyrimidines as anticancer agents | WYETH (US) | 2008-02-12 | — | — | US | disclosed |
| US-7223778-B2 | 5-substituted-2-arylpyridines | NEUROGEN CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1606380-B1 | DETERGENT COMPOSITIONS | CIBA SC HOLDING AG (CH) | 2007-04-11 | — | — | EP | disclosed |