Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.52 |
| ▸ | FNTB | P49356 | 15/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937336 | 0.91 | FNTA (0.56) | FNTAFNTBPGGT1BKCNH2BRS3 | |
| SCHEMBL7936234 | 0.87 | FNTA (0.64) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7927530 | 0.82 | BRS3 (0.41) | FNTAFNTBPGGT1BKCNH2BRS3 | |
| SCHEMBL7939460 | 0.76 | PSEN1 (0.37) | FNTAFNTBPGGT1BBRS3 | |
| SCHEMBL7927492 | 0.74 | BRS3 (0.37) | BRS3DPP4 | |
| SCHEMBL7937345 | 0.72 | FNTA (0.79) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7936645 | 0.71 | FNTA (0.79) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7936080 | 0.70 | FNTA (0.72) | FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL7935741 | 0.69 | FNTA (0.42) | FNTAFNTBPGGT1BKCNH2BRS3 | |
| SCHEMBL7936751 | 0.69 | FNTA (0.37) | FNTAFNTBPGGT1BBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |