Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132888 | 0.84 | EPHX1 (0.63) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL2132882 | 0.84 | EPHX1 (0.63) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL7881494 | 0.84 | EPHX1 (0.63) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL23573505 | 0.84 | EPHX1 (0.68) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL2131537 | 0.84 | EPHX1 (0.68) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL23573324 | 0.84 | EPHX1 (0.68) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL16358910 | 0.82 | EPHX1 (0.64) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL17875071 | 0.82 | EPHX1 (0.78) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL12655781 | 0.81 | EPHX1 (0.58) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A | |
| SCHEMBL2131950 | 0.80 | EPHX1 (0.57) | EPHX1ACHEL3MBTL3L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245796-B1 | NERVOUS SYSTEM DISORDERS; SEXUAL DISORDERS; SLEEP DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0990650-A1 | TRICYCLIC PYRROLE OR PYRAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |