SCHEMBL7936865

SCHEMBL7936865

CCc1cccc(C2=CC(C)C([Hf](=[GeH2])(C3=C(C)C(c4cccc(CC)c4)=CC3C)(c3ccccc3)c3ccccc3)=C2C)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.35
PTGS2 P35354 1/20 0.32
IDO1 P14902 1/20 0.32
TP53 P04637 1/20 0.31
NISCH Q9Y2I1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7933076 0.88 BCL2 (0.33) BCL2PTGS2IDO1
Hydrochloric Acid SCHEMBL7938816 0.84 BCL2 (0.34) BCL2PTGS2IDO1TP53NISCH
Hydrochloric Acid SCHEMBL7745958 0.84 BCL2 (0.34) BCL2PTGS2IDO1NISCH
Hydrochloric Acid SCHEMBL7926614 0.84 BCL2 (0.34) BCL2PTGS2IDO1NISCH
Hydrochloric Acid SCHEMBL7933135 0.79 BCL2 (0.34) BCL2PTGS2IDO1NISCH
Hydrochloric Acid SCHEMBL7935720 0.72 BCL2 (0.39) BCL2PTGS2IDO1TP53NISCH
Hydrochloric Acid SCHEMBL7933012 0.72 BCL2 (0.38) BCL2PTGS2IDO1NISCH
Hydrochloric Acid SCHEMBL7939105 0.71
SCHEMBL7936864 0.70 BCL2 (0.34) BCL2PTGS2IDO1TP53NISCH
Hydrochloric Acid SCHEMBL7938814 0.69 BCL2 (0.33) BCL2PTGS2IDO1NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed