⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243017 | 0.87 | TSHR (0.35) | — | |
| SCHEMBL621783 | 0.86 | TSHR (0.50) | — | |
| SCHEMBL617879 | 0.86 | TSHR (0.50) | — | |
| SCHEMBL3693113 | 0.84 | TSHR (0.50) | — | |
| SCHEMBL3693109 | 0.84 | TSHR (0.50) | — | |
| SCHEMBL3666728 | 0.82 | TSHR (0.54) | — | |
| SCHEMBL22117219 | 0.82 | — | — | |
| SCHEMBL284709 | 0.78 | — | — | |
| SCHEMBL9851996 | 0.77 | — | — | |
| SCHEMBL9851998 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | disclosed |
| CN-115708891-A | Developing drug-loaded microsphere based on microfluidic technology and preparation method and application thereof | 四川大学 | 2023-02-24 | — | — | CN | disclosed |
| EP-3331880-B1 | N-(PYRIDIN-2-YL)-4-(THIAZOL-5-YL)PYRIMIDIN-2-AMINE DERIVATIVES AS THERAPEUTIC COMPOUNDS | AUCENTRA THERAPEUTICS PTY LTD (AU) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020233677-A1 | PROCESS FOR PREPARING AMIDE-SUBSTITUTED IMIDAZO COMPOUNDS | BEIGENE (BEIJING) CO., LTD. (CN) | 2020-11-26 | — | — | WO | disclosed |
| WO-2018026620-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-02-08 | — | — | WO | disclosed |
| WO-2017160925-A1 | ANALGESIC COMPOUNDS | KALYRA PHARMACEUTICALS, INC. (US) | 2017-09-21 | — | — | WO | disclosed |
| WO-2017075522-A2 | GLP-2 POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017075505-A2 | NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |
| EP-3124551-A1 | RHODAMINE-BASED COLORING COMPOSITION | Wako Pure Chemical Industries, Ltd. (JP) | 2017-02-01 | — | — | EP | disclosed |
| CN-1215042-C | Process for preparing alkylamines | BASF AG (DE) | 2005-08-17 | — | — | CN | disclosed |
| CN-1438987-A | Process for preparing alkylamines | BASF AG (DE) | 2003-08-27 | — | — | CN | disclosed |
| EP-1086173-A1 | THERMOPLASTIC NANOCOMPOSITES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999060057-A1 | THERMOPLASTIC NANOCOMPOSITES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |