Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.50 |
| ▸ | FNTB | P49356 | 14/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936114 | 0.77 | SLC6A4 (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7937082 | 0.77 | SLC6A4 (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7936119 | 0.77 | SLC6A4 (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7933703 | 0.77 | FNTA (0.56) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7933845 | 0.77 | FNTA (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7933707 | 0.77 | FNTA (0.56) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7933841 | 0.77 | FNTA (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7939485 | 0.74 | FNTA (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7939484 | 0.74 | FNTA (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7939464 | 0.71 | FNTA (0.68) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |