Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950186 | 1.00 | BACE1 (0.63) | BACE1 | |
| SCHEMBL7946255 | 0.91 | BACE1 (0.64) | BACE1 | |
| SCHEMBL7943531 | 0.89 | BACE1 (0.63) | BACE1 | |
| SCHEMBL7942893 | 0.84 | BACE1 (0.55) | BACE1 | |
| SCHEMBL7944611 | 0.82 | BACE1 (0.56) | BACE1 | |
| SCHEMBL7938124 | 0.82 | BACE1 (0.56) | BACE1 | |
| SCHEMBL7944379 | 0.82 | BACE1 (0.54) | BACE1 | |
| SCHEMBL7950198 | 0.82 | BACE1 (0.63) | BACE1 | |
| SCHEMBL7947180 | 0.82 | BACE1 (0.63) | BACE1 | |
| SCHEMBL7947987 | 0.80 | BACE1 (0.60) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |