⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16155294 | 0.74 | — | — | |
| SCHEMBL256978 | 0.63 | — | — | |
| SCHEMBL18699199 | 0.61 | — | — | |
| SCHEMBL10981439 | 0.59 | — | — | |
| SCHEMBL10074741 | 0.58 | — | — | |
| SCHEMBL10050831 | 0.58 | — | — | |
| SCHEMBL10370753 | 0.57 | — | — | |
| SCHEMBL11259921 | 0.57 | — | — | |
| SCHEMBL16024475 | 0.57 | — | — | |
| SCHEMBL18381475 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014164195-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC (US) | 2014-10-09 | — | — | WO | disclosed |
| US-8394427-B2 | Paxillin stimulating compositions and cosmetic uses thereof | AVON PRODUCTS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120328546-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-20110151029-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2010019391-A1 | N-HETEROCYCLIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-02-18 | — | — | WO | disclosed |