Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7937433

N.N.Nc1cccc(Oc2cccc(N)c2)c1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.82
MAPT P10636 2/20 0.63
POLB P06746 1/20 0.63
HSP90AA1 P07900 1/20 0.63
ALDH1A1 P00352 5/20 0.62
CYP3A4 P08684 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
MITF O75030 1/20 0.62
GAA P10253 1/20 0.62
GFER P55789 1/20 0.62
NLRP1 Q9C000 1/20 0.62
NOD2 Q9HC29 1/20 0.62
ATM Q13315 1/20 0.56
TP53 P04637 1/20 0.56
CASP1 P29466 1/20 0.55
RECQL P46063 1/20 0.55
LTA4H P09960 1/20 0.49
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8193692 0.97 MAOB (0.78) MAOBMAPTPOLBHSP90AA1ALDH1A1
Ammonia Solution, Strong SCHEMBL9484664 0.97 MAOB (0.78) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL55303 0.97 MAOB (0.86) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL30107929 0.97 MAOB (0.86) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL29414092 0.97 MAOB (0.86) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL6289774 0.95 MAOB (0.82) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL4455312 0.95 MAOB (0.82) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL84301 0.95 MAOB (0.82) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL310904 0.95 MAOB (0.82) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL1271035 0.95 MAOB (0.82) MAOBMAPTPOLBHSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6246102-B1 Integrated circuits, transistors, data processing systems, printed wiring boards, digital computers, smart power devices, and processes of manufacture TEXAS INSTRUMENTS INCORPORATED 2001-06-12 US disclosed
EP-0478368-B1 Integrated circuits and processes of manufacture TEXAS INSTRUMENTS INC (US) 1997-12-03 EP disclosed
US-5689428-A Integrated circuits, transistors, data processing systems, printed wiring boards, digital computers, smart power devices, and processes of manufacture TEXAS INSTRUMENTS INCORPORATED (US) 1997-11-18 US disclosed
EP-0478368-A1 Integrated circuits and processes of manufacture TEXAS INSTRUMENTS INCORPORATED (US) 1992-04-01 EP disclosed