Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 4/20 | 0.47 |
| ▸ | FNTB | P49356 | 4/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937461 | 1.00 | HDAC1 (0.56) | HDAC1HDAC8HDAC6FNTAFNTB | |
| Hydrochloric Acid SCHEMBL7927540 | 0.98 | HDAC1 (0.55) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL14171435 | 0.90 | NPY1R (0.52) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL12797532 | 0.90 | NPY1R (0.52) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL14171602 | 0.87 | HDAC1 (0.48) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL14171722 | 0.82 | HPGD (0.43) | HDAC1HDAC8HDAC6F10HPGD | |
| SCHEMBL13547184 | 0.82 | HDAC1 (0.46) | HDAC1HDAC8HDAC6HPGDTSHR | |
| SCHEMBL14172059 | 0.81 | HDAC1 (0.43) | HDAC1HDAC8HDAC6HPGDTSHR | |
| SCHEMBL15966510 | 0.80 | HDAC1 (0.56) | HDAC1HDAC8HDAC6FPR2ACE | |
| SCHEMBL14171662 | 0.80 | MEN1 (0.43) | HDAC1HDAC8HDAC6KCNH2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |