Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.64 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.64 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.64 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.64 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.64 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.64 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712308 | 1.00 | PPARG (0.64) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7929605 | 0.89 | PPARG (0.65) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7632829 | 0.87 | PPARG (0.48) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7942618 | 0.86 | PPARG (0.47) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7929607 | 0.86 | PPARG (0.67) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7929608 | 0.86 | PPARG (0.67) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7632053 | 0.85 | CYP1A2 (0.47) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7638531 | 0.84 | PPARG (0.48) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL7635986 | 0.84 | PPARG (0.48) | PPARGCYP1A2MAPTMAPK1PTGS1 | |
| SCHEMBL8154644 | 0.84 | MAPT (0.46) | PPARGCYP1A2MAPTMAPK1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |