Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LRAT | O95237 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FGF1 | P05230 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28127820 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRBLMRECQLTDP1 | |
| Acetic Acid SCHEMBL15526592 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRBLMRECQLTDP1 | |
| Acetic Acid SCHEMBL7935270 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL8886136 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL19090413 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL24372177 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL19074569 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL8886131 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL21916330 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 | |
| SCHEMBL23259481 | 0.92 | TSHR (0.57) | HSD17B10TSHRBLMRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110881426-B | Pond mixed culture method for grouper and white shrimps | 海南晨海水产有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-110881426-A | Pond mixed culture method for grouper and white shrimps | 海南晨海水产有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-107347939-A | A kind of fish shrimp crab raises together pool killing pests and suppressing bacteria agent and its application | 安徽省黄淮兽药有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-110881426-B | Pond mixed culture method for grouper and white shrimps | 海南晨海水产有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110881426-A | Pond mixed culture method for grouper and white shrimps | 海南晨海水产有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-107347939-A | A kind of fish shrimp crab raises together pool killing pests and suppressing bacteria agent and its application | 安徽省黄淮兽药有限公司 | 2017-11-17 | — | — | CN | disclosed |
| US-6242431-B1 | Method for treating liver dysfunction | YAIZU SUISANKAGAKU INDUSTRY CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5981510-A | ADMINISTERING COMPOUNDS SELECTED FROM CHITIN OLIGOSACCHARIDES, CHITOSAN OLIGOSACCHARIDE AND THEIR SALTS TO TREAT NON-INSULIN DEPENDENT DIABETIC PATIENTS | YAIZU SUISANKAGAKU INDUSTRY CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |