Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447443 | 0.81 | PBRM1 (0.44) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL22982478 | 0.79 | MEN1 (0.56) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL29661202 | 0.79 | MEN1 (0.56) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL7624438 | 0.74 | PBRM1 (0.44) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL8308277 | 0.71 | MEN1 (0.51) | MEN1MAPK1KMT2ANPSR1HSD17B1 | |
| SCHEMBL27691769 | 0.68 | MEN1 (0.56) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL20681358 | 0.68 | MEN1 (0.54) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL6915238 | 0.65 | MEN1 (0.51) | MEN1MAPK1KMT2ANPSR1HSD17B1 | |
| SCHEMBL11111147 | 0.63 | MEN1 (0.59) | MEN1MAPK1KMT2ANPSR1PBRM1 | |
| SCHEMBL179913 | 0.63 | MEN1 (0.64) | MEN1MAPK1KMT2ANPSR1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946575-B1 | FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW CHEMICAL CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6034022-A | COORDINATION POLYMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| US-5965756-A | COORDINATION CATALYSTS AS ADDITION POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0946575-A1 | FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027103-A1 | FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |