Triaziquone

Triaziquone

SCHEMBL7938206

CCCCCCO.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
TP53 P04637 2/20 0.36
MAPT P10636 2/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
DNMT1 P26358 1/20 0.34
ALOX5 P09917 11/20 0.34
MPEG1 Q2M385 8/20 0.34
XIAP P98170 2/20 0.34
GPR84 Q9NQS5 2/20 0.34
NSD2 O96028 1/20 0.34
TTR P02766 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PTGES O14684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL9798150 0.94 TP53 (0.37) ALDH1A1SMN1; SMN2TP53MAPTSTAT3
Triaziquone SCHEMBL6387848 0.84 MAPT (0.41) LMNAALDH1A1MEN1KMT2ATSHR
Triaziquone SCHEMBL11744543 0.82 PPARG (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
Stearic Acid SCHEMBL11745947 0.82 PPARG (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
Triaziquone SCHEMBL11745026 0.82 PPARG (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
Triaziquone SCHEMBL1846206 0.81 CA1 (0.36) TSHRSMN1; SMN2TP53MAPTSTAT3
Stearic Acid SCHEMBL17653805 0.81 PPARG (0.41) LMNAALDH1A1HSD17B10MEN1KMT2A
Triaziquone SCHEMBL11270803 0.81 TP53 (0.36) SMN1; SMN2TP53MAPTSTAT3HTT
Triaziquone SCHEMBL3721145 0.80 NSD2 (0.35) SMN1; SMN2TP53MAPTSTAT3HTT
Triaziquone SCHEMBL1961248 0.80 DNMT1 (0.39) MEN1KMT2ATSHRSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1093489-A1 CROSS-LINKABLE POLYMER POWDER COMPOSITIONS Wacker-Chemie GmbH (DE) 2001-04-25 EP disclosed
WO-1999067325-A1 CROSS-LINKABLE POLYMER POWDER COMPOSITIONS WACKER-CHEMIE GMBH (DE) 1999-12-29 WO disclosed