Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.57 |
| ▸ | CCR3 | P51677 | 4/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934814 | 0.88 | TACR1 (0.60) | TACR1CCR3CCR2 | |
| SCHEMBL7932658 | 0.87 | TACR1 (0.56) | TACR1CCR3CCR2 | |
| SCHEMBL6478424 | 0.87 | TACR1 (0.74) | TACR1CCR3 | |
| SCHEMBL7986183 | 0.87 | TACR1 (0.74) | TACR1CCR3 | |
| SCHEMBL7925947 | 0.87 | TACR1 (0.58) | TACR1CCR3CCR2 | |
| SCHEMBL7934839 | 0.86 | TACR1 (0.73) | TACR1CCR3 | |
| SCHEMBL6479126 | 0.86 | TACR1 (0.54) | TACR1CCR3CCR2 | |
| SCHEMBL7938507 | 0.85 | TACR1 (0.60) | TACR1CCR3CCR2 | |
| SCHEMBL7926175 | 0.85 | TACR1 (0.72) | TACR1CCR3 | |
| SCHEMBL7936492 | 0.84 | TACR1 (0.57) | TACR1CCR3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |
| WO-1996008480-A1 | NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1996-03-21 | — | — | WO | disclosed |