Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.66 |
| ▸ | TACR1 | P25103 | 7/20 | 0.62 |
| ▸ | MC4R | P32245 | 2/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925817 | 0.93 | TACR1 (0.62) | CCR3TACR1 | |
| SCHEMBL7925820 | 0.91 | TACR1 (0.59) | CCR3TACR1 | |
| SCHEMBL7989743 | 0.88 | CCR3 (0.57) | CCR3TACR1 | |
| SCHEMBL7934923 | 0.88 | CCR3 (0.76) | CCR3TACR1 | |
| SCHEMBL7926239 | 0.87 | TACR1 (0.59) | CCR3TACR1 | |
| SCHEMBL7989699 | 0.87 | TACR1 (0.64) | CCR3TACR1 | |
| SCHEMBL7925949 | 0.87 | CCR3 (0.61) | CCR3TACR1 | |
| SCHEMBL7925950 | 0.87 | CCR3 (0.77) | CCR3TACR1 | |
| SCHEMBL7932773 | 0.87 | CCR3 (0.77) | CCR3TACR1 | |
| SCHEMBL7934695 | 0.87 | TACR1 (0.58) | CCR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |