Methacrylic Acid

Methacrylic Acid

SCHEMBL7938564

C=C(C)C(=O)O.CCC(O)COCCOCCOCCO

nearest known ligand 0.35

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.35
USP2 O75604 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ALOX15 P16050 1/20 0.35
THRB P10828 2/20 0.35
HTT P42858 2/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 3/20 0.33
HSD17B10 Q99714 1/20 0.32
MAPK1 P28482 1/20 0.32
PLA2G2C Q5R387 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL161187 1.00 MEN1 (0.35) MEN1KMT2AALDH1A1USP2KDM4E
Methacrylic Acid SCHEMBL6402976 0.97 USP2 (0.37) ALDH1A1USP2KDM4EALOX15THRB
Acetic Acid SCHEMBL27436234 0.86 USP2 (0.40) MEN1KMT2AALDH1A1USP2KDM4E
Methacrylic Acid SCHEMBL6427815 0.85 MEN1 (0.37) MEN1KMT2ATHRBHTTMAPT
Methacrylic Acid SCHEMBL29037257 0.85 TSHR (0.56) MEN1KMT2AALDH1A1USP2KDM4E
Methacrylic Acid SCHEMBL6048438 0.85 MEN1 (0.39) MEN1KMT2AALDH1A1USP2KDM4E
Bicarbonate SCHEMBL11631796 0.84 USP2 (0.41) MEN1KMT2AALDH1A1USP2KDM4E
SCHEMBL7936542 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1USP2KDM4E
SCHEMBL21069867 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1USP2KDM4E
SCHEMBL12311686 0.84 MEN1 (0.50) MEN1KMT2AALDH1A1USP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0960137-B1 MOLECULAR WEIGHT TRUNCATION AND COLOR CONTROL IN MACROMONOMERS DU PONT (US) 2001-11-28 EP disclosed
EP-0960137-A1 MOLECULAR WEIGHT TRUNCATION AND COLOR CONTROL IN MACROMONOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-12-01 EP disclosed
WO-1998033824-A1 MOLECULAR WEIGHT TRUNCATION AND COLOR CONTROL IN MACROMONOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-08-06 WO disclosed
US-5726263-A CATALYTIC CHAIN TRANSFER POLYMERIZATION OF ACRYLIC MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-10 US disclosed