Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290619 | 0.90 | PARP10 (0.50) | SLC6A4SLC6A2SLC6A3HTR1APARP10 | |
| SCHEMBL6290334 | 0.90 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL6290439 | 0.88 | PARP10 (0.49) | SLC6A4SLC6A2SLC6A3HTR1APARP10 | |
| SCHEMBL6290672 | 0.88 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL6293813 | 0.88 | PARP10 (0.49) | SLC6A4SLC6A2SLC6A3HTR1APARP10 | |
| SCHEMBL6293111 | 0.88 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL6290645 | 0.88 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL6289259 | 0.88 | PARP10 (0.49) | SLC6A4SLC6A2SLC6A3HTR1APARP10 | |
| SCHEMBL6290492 | 0.88 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL6289809 | 0.86 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |