SCHEMBL7939201

SCHEMBL7939201

COc1cc(O)ccc1C(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.64
MAPK1 P28482 4/20 0.64
KDM4E B2RXH2 3/20 0.64
HSD17B10 Q99714 3/20 0.64
ALOX15 P16050 1/20 0.64
LMNA P02545 7/20 0.62
HPGD P15428 4/20 0.62
HTT P42858 3/20 0.62
ALDH1A1 P00352 3/20 0.62
CYP3A4 P08684 2/20 0.62
RECQL P46063 2/20 0.62
CYP1A2 P05177 2/20 0.62
CYP2D6 P10635 2/20 0.62
CYP2C19 P33261 2/20 0.62
PGR P06401 1/20 0.62
SLC6A2 P23975 1/20 0.62
PDE4A P27815 1/20 0.62
HRH1 P35367 1/20 0.62
SLC6A3 Q01959 1/20 0.62
PDE4D Q08499 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758323 0.90 MAPT (0.68) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL4049476 0.87 MAPT (0.64) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL1758262 0.86 MAOB (0.58) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL27850225 0.85 MAPT (0.72) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL25333107 0.84 KMT2A (0.58) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL27182876 0.84 CDC25B (0.61) KDM4EHSD17B10ALOX15LMNAHPGD
SCHEMBL3224251 0.83 NPC1 (0.81) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL257274 0.83 MAPT (0.62) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL30205105 0.83 NPC1 (0.81) MAPTMAPK1KDM4EHSD17B10ALOX15
SCHEMBL895985 0.83 KMT2A (0.51) MAPTMAPK1KDM4EHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590976-B Poly-p-hydroxystyrene derivative containing azo group, preparation method thereof and application thereof in anti-reflection coating 北京师范大学 2020-12-25 CN disclosed
CN-110590976-A Poly-p-hydroxystyrene derivative containing azo group, preparation method thereof and application thereof in anti-reflection coating 北京师范大学 2019-12-20 CN disclosed
EP-0846672-B1 Process for the synthesis of 2-hydroxy-4-alkyloxy benzophenone ENICHEM SPA (IT) 2001-07-25 EP disclosed
US-5849955-A Process for the synthesis of 2-hydroxy-4-alkyloxy benzophenone ENICHEM S.P.A. (IT) 1998-12-15 US disclosed
EP-0846672-A1 Process for the synthesis of 2-hydroxy-4-alkyloxy benzophenone ENICHEM S.p.A. (IT) 1998-06-10 EP disclosed
EP-0442068-B1 Benzophenone derivatives and polymers containing phenolic hydroxyl groups BAYER AG (DE) 1994-06-08 EP disclosed
EP-0442068-A2 Benzophenone derivatives and polymers containing phenolic hydroxyl groups BAYER AG (DE) 1991-08-21 EP disclosed
EP-0066990-B1 PROCESS FOR PRODUCTION OF PRESENSITIZED LITHOGRAPHIC PRINTING PLATES KONICA CORPORATION (JP) 1986-03-05 EP disclosed
EP-0066990-A2 Process for production of presensitized lithographic printing plates KONICA CORPORATION (JP) 1982-12-15 EP disclosed