Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.43 |
| ▸ | TUBB | P07437 | 8/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938338 | 1.00 | PTAFR (0.44) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7938340 | 1.00 | PTAFR (0.44) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6359533 | 0.76 | CHRNB4 (0.47) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10578730 | 0.67 | PTAFR (0.55) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9719096 | 0.67 | PTAFR (0.55) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9719091 | 0.67 | PTAFR (0.55) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9719101 | 0.67 | PTAFR (0.55) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9719044 | 0.67 | PTAFR (0.55) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9719054 | 0.67 | PTAFR (0.55) | PTAFRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9719087 | 0.67 | PTAFR (0.58) | PTAFRTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248752-B1 | Azabicyclooctane compositions and methods for enhancing chemotherapy | SMITH CHARLES DUANE (US) | 2001-06-19 | — | — | US | claimed |
| US-6248752-B1 | Azabicyclooctane compositions and methods for enhancing chemotherapy | SMITH CHARLES DUANE (US) | 2001-06-19 | — | — | US | disclosed |