Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793029 | 0.94 | TYK2 (0.63) | TYK2JAK2 | |
| SCHEMBL793062 | 0.94 | TYK2 (0.58) | TYK2JAK2 | |
| SCHEMBL792703 | 0.93 | TYK2 (0.62) | TYK2JAK2 | |
| SCHEMBL793063 | 0.90 | TYK2 (0.66) | TYK2JAK2 | |
| SCHEMBL11960363 | 0.88 | TYK2 (0.66) | TYK2JAK2 | |
| SCHEMBL793328 | 0.88 | TYK2 (0.55) | TYK2JAK2 | |
| SCHEMBL793290 | 0.87 | TYK2 (0.66) | TYK2JAK2 | |
| SCHEMBL793152 | 0.86 | TYK2 (0.70) | TYK2JAK2 | |
| SCHEMBL793484 | 0.85 | TYK2 (0.67) | TYK2JAK2 | |
| SCHEMBL11960366 | 0.85 | TYK2 (0.58) | TYK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616072-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035039-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-22 | — | — | WO | disclosed |