SCHEMBL7939626

SCHEMBL7939626

CCC(CC)CC(C(=O)O)C(=O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
RNPEP Q9H4A4 1/20 0.30
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008665 0.85 SLC1A3 (0.41) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL3504770 0.79 CHRM1 (0.38) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL3226142 0.77 CHRM1 (0.36) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL16273577 0.75 RNPEP (0.48) SLC1A3SLC1A2ADRA1ARNPEPSLC7A5
SCHEMBL19690591 0.72 SLC1A3 (0.39) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL247454 0.70 FFAR3 (0.32) CA2MAPK1TDP1
SCHEMBL12950308 0.70 SLC1A2 (0.60) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL2696819 0.70 NAALAD2 (0.46) SLC1A3SLC1A2SLC1A1HDAC1HDAC2
SCHEMBL21269286 0.70 CHRM1 (0.46) SLC1A3SLC1A2SLC1A1CA2MAPK1
SCHEMBL21269807 0.70 CHRM1 (0.46) SLC1A3SLC1A2SLC1A1CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926127-B1 Process for the preparation of acyclic alpha,beta-dicarbonyl compounds CLARIANT FRANCE SA (FR) 2001-10-04 EP disclosed
US-6057474-A DIKETONE OR KETONE ESTER REACTED WITH OXYGEN AND NITRILE SOLVENT CLARIANT S.A. (FR) 2000-05-02 US disclosed
EP-0926127-A1 Process for the preparation of acyclic alpha,beta-dicarbonyl compounds Clariant (France) S.A. (FR) 1999-06-30 EP disclosed