Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055913 | 0.90 | ELANE (0.65) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL10013424 | 0.87 | ELANE (0.61) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL8344863 | 0.86 | ELANE (0.83) | ELANECYP2C9ADRB1HTR1AHRH3 | |
| SCHEMBL14760555 | 0.86 | ELANE (0.83) | ELANECYP2C9ADRB1HTR1AHRH3 | |
| SCHEMBL7903282 | 0.83 | ELANE (0.63) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL7901491 | 0.83 | ELANE (0.62) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL7906666 | 0.83 | ELANE (0.62) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL10013432 | 0.83 | ELANE (0.62) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL10041854 | 0.83 | ELANE (0.62) | ELANECYP2C9LMNARECQLADRB1 | |
| SCHEMBL17343235 | 0.82 | KMT2A (0.58) | ELANECYP2C9LMNARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034996-A1 | CRYSTALLINE ACID ADDITION SALTS AND THEIR USE AS ENZYME INHIBITORS | ARGENTA DISCOVERY 2009 LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |