Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937486 | 0.87 | MEN1 (0.33) | PPARGMEN1KMT2ARXRACYP1A2 | |
| SCHEMBL7930958 | 0.85 | PPARG (0.35) | PPARGMEN1KMT2ARXRACYP1A2 | |
| SCHEMBL8681338 | 0.84 | PPARG (0.38) | PPARGMEN1KMT2ARXRACYP1A2 | |
| SCHEMBL7632790 | 0.83 | LRRK2 (0.38) | PPARGRXRACYP1A2GLACYP3A4 | |
| SCHEMBL5712317 | 0.83 | PPARG (0.48) | PPARGMEN1KMT2ARXRACYP1A2 | |
| SCHEMBL5712320 | 0.83 | PPARG (0.48) | PPARGMEN1KMT2ARXRACYP1A2 | |
| SCHEMBL7632973 | 0.83 | CYP1A2 (0.47) | PPARGCYP1A2GLACYP3A4MAPT | |
| SCHEMBL7632675 | 0.83 | PPARG (0.39) | PPARGMEN1KMT2ARXRAMAPT | |
| SCHEMBL9710902 | 0.82 | PPARG (0.42) | PPARGMEN1KMT2ARXRACYP1A2 | |
| SCHEMBL7639124 | 0.80 | RET (0.34) | PPARGKMT2ARXRAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |