Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12650057 | 0.93 | TRIM24 (0.55) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL10564328 | 0.84 | TRIM24 (0.39) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL7941523 | 0.84 | KMT2A (0.46) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL4416309 | 0.84 | KMT2A (0.46) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL4415563 | 0.81 | KMT2A (0.54) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL7934086 | 0.81 | KMT2A (0.54) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL2197936 | 0.81 | KMT2A (0.54) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL2691441 | 0.81 | KMT2A (0.54) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL6243018 | 0.80 | KMT2A (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 | |
| SCHEMBL6243332 | 0.80 | KMT2A (0.58) | TRIM24TRIM33ALDH1A1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102736-A2 | PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES | QUEST INTERNATIONAL B.V. (NL) | 2001-05-30 | — | — | EP | disclosed |
| EP-0976714-A1 | Addition of ketones to alkenes | QUEST INTERNATIONAL B.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-2000001648-A2 | PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES | QUEST INTERNATIONAL B.V. (NL) | 2000-01-13 | — | — | WO | disclosed |