Methoxyphenone

Methoxyphenone

SCHEMBL7940579

COc1ccc(C(=O)c2cccc(C)c2)cc1C.O=C(c1ccccc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.57
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
CYP2D6 P10635 1/20 0.55
HPGD P15428 1/20 0.55
POLB P06746 3/20 0.53
MAPT P10636 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
CTNNB1 P35222 1/20 0.51
WNT3A P56704 1/20 0.51
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
CNR1 P21554 1/20 0.49
ACHE P22303 1/20 0.48
ADORA3 P0DMS8 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxyphenone SCHEMBL51436 0.90 CTNNB1 (0.60) CNR2CYP1A2CYP2C19CYP2D6HPGD
Methoxyphenone SCHEMBL30116856 0.90 CTNNB1 (0.60) CNR2CYP1A2CYP2C19CYP2D6HPGD
Methoxyphenone SCHEMBL29419110 0.90 CTNNB1 (0.60) CNR2CYP1A2CYP2C19CYP2D6HPGD
Methoxyphenone SCHEMBL29456709 0.90 CTNNB1 (0.60) CNR2CYP1A2CYP2C19CYP2D6HPGD
SCHEMBL9360017 0.87 CYP1A2 (0.69) CYP1A2CYP2C19CYP2D6HPGDMAPT
Methoxyphenone SCHEMBL28082194 0.86 CNR2 (0.45) CNR2CYP1A2CYP2C19CYP2D6HPGD
SCHEMBL194537 0.86 CNR2 (0.69) CNR2HPGDPOLBMAPTCTDSP1
SCHEMBL29490805 0.86 CNR2 (0.69) CNR2HPGDPOLBMAPTCTDSP1
Methoxyphenone SCHEMBL7559843 0.85 CYP1A2 (0.50) CNR2CYP1A2CYP2C19CYP2D6HPGD
SCHEMBL5606155 0.83 CNR2 (0.66) CNR2HPGDPOLBMAPTCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235433-B1 HIGH MOLECULAR WEIGHT GEL ELECTROLYTE NEC CORPORATION (JP) 2001-05-22 US disclosed