Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 20/20 | 0.79 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1294330 | 1.00 | CMA1 (0.79) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL7948931 | 0.93 | CMA1 (0.81) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL1294819 | 0.93 | CMA1 (0.81) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL1295112 | 0.91 | CMA1 (0.66) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL2696235 | 0.88 | CMA1 (1.00) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL2309639 | 0.87 | CMA1 (0.75) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL2314595 | 0.87 | CMA1 (0.75) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL2309191 | 0.87 | CMA1 (0.75) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL2311128 | 0.86 | CMA1 (0.73) | CMA1HTR1DOPRK1CTSG | |
| SCHEMBL3261759 | 0.85 | CMA1 (0.70) | CMA1HTR1DOPRK1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030500-A1 | AZA-BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-18 | — | — | WO | disclosed |