Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588917 | 0.91 | MRGPRX4 (0.40) | MRGPRX4PTGER1XDHSLC6A9CYP19A1 | |
| SCHEMBL6591101 | 0.81 | MRGPRX4 (0.39) | MRGPRX4PTGER1XDHSLC6A9CYP19A1 | |
| SCHEMBL6591887 | 0.81 | MRGPRX4 (0.38) | MRGPRX4PTGER1XDHSLC6A9CYP19A1 | |
| SCHEMBL7420284 | 0.81 | MRGPRX4 (0.38) | MRGPRX4PTGER1XDHSLC6A9PPIA | |
| SCHEMBL6590066 | 0.81 | MRGPRX4 (0.38) | MRGPRX4PTGER1XDHSLC6A9CYP19A1 | |
| SCHEMBL6595090 | 0.80 | MRGPRX4 (0.39) | MRGPRX4PTGER1XDHSLC6A9CYP19A1 | |
| SCHEMBL6596992 | 0.80 | MRGPRX4 (0.39) | MRGPRX4PTGER1XDHSLC6A9PPIA | |
| SCHEMBL6595958 | 0.80 | MRGPRX4 (0.38) | MRGPRX4PTGER1XDHSLC6A9CYP19A1 | |
| SCHEMBL7415762 | 0.80 | MAPT (0.38) | MRGPRX4PTGER1SLC6A9NPC1RAB9A | |
| SCHEMBL7492184 | 0.80 | MRGPRX4 (0.38) | MRGPRX4PTGER1XDHSLC6A9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242454-B1 | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants | BERLEX LABORATORIES INC. | 2001-06-05 | — | — | US | disclosed |