Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129592 | 0.89 | PDE4A (0.51) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL3122519 | 0.86 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3121195 | 0.84 | PDE4A (0.49) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3128686 | 0.81 | PDE4A (0.43) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL1157704 | 0.81 | PDE4A (0.61) | PDE4APDE4DPDE4BPDE4CGRM2 | |
| SCHEMBL4191109 | 0.80 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL1157553 | 0.80 | PDE4A (0.53) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL1157333 | 0.79 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL3122620 | 0.79 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4CTP53 | |
| SCHEMBL4193004 | 0.79 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |