Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CPS1 | P31327 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366735 | 0.88 | MEN1 (0.46) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL2366086 | 0.83 | KDM4E (0.39) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL2365868 | 0.80 | GRM5 (0.41) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL2367055 | 0.79 | KDM4E (0.39) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL2367049 | 0.79 | KDM4E (0.39) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL2366635 | 0.79 | PANK3 (0.44) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL27848379 | 0.77 | PANK3 (0.54) | KDM4ELMNAHTTSMN1; SMN2PANK3 | |
| SCHEMBL2365852 | 0.74 | PANK3 (0.38) | KDM4ELMNASMN1; SMN2PANK3ALDH1A1 | |
| SCHEMBL22172321 | 0.74 | MEN1 (0.55) | KDM4ELMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL21245854 | 0.73 | CPS1 (0.49) | KDM4ESMN1; SMN2KMT2AMEN1CPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050461-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | 田辺三菱製薬株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |