Indole

Indole

SCHEMBL7941445

Cc1c[nH]c2ccccc12.N.c1ccc2[nH]ccc2c1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.69
AHR P35869 2/20 0.59
TRPA1 O75762 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
ITGB2 P05107 1/20 0.59
ICAM1 P05362 1/20 0.59
ITGAL P20701 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
ADK P55263 1/20 0.59
IMPDH2 P12268 1/20 0.41
IMPDH1 P20839 1/20 0.41
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 2/20 0.40
ALOX15 P16050 2/20 0.40
MC5R P33032 1/20 0.40
MC1R Q01726 1/20 0.40
HPGD P15428 1/20 0.40
CFTR P13569 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL1821121 0.98 ATM (0.71) ATMAHRTRPA1CA1CA2
Indole SCHEMBL9436374 0.98 ATM (0.71) ATMAHRTRPA1CA1CA2
Ammonia Solution, Strong SCHEMBL9066277 0.85 ATM (0.95) ATMAHRIMPDH2IMPDH1HSD17B10
Indole SCHEMBL27896442 0.84 ATM (0.53) ATMAHRTRPA1CA1CA2
SCHEMBL366553 0.83 ATM (1.00) ATMAHRIMPDH2IMPDH1HSD17B10
SCHEMBL5396 0.83 ATM (1.00) ATMAHRIMPDH2IMPDH1HSD17B10
SCHEMBL29520285 0.81 ATM (0.95) ATMAHRIMPDH2IMPDH1HSD17B10
Hydrochloric Acid SCHEMBL29291150 0.81 ATM (0.95) ATMAHRIMPDH2IMPDH1HSD17B10
Methane SCHEMBL29137522 0.81 ATM (0.95) ATMAHRIMPDH2IMPDH1HSD17B10
SCHEMBL28222677 0.81 ATM (0.95) ATMAHRIMPDH2IMPDH1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082149-A1 ENHANCED ODOR ABSORPTION BY NATURAL AND SYNTHETIC POLYMERS Kimberly-Clark Worldwide, Inc. (US) 2001-03-14 EP disclosed
WO-1999061079-A1 ENHANCED ODOR ABSORPTION BY NATURAL AND SYNTHETIC POLYMERS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-12-02 WO disclosed