Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193721 | 1.00 | KMT2A (0.57) | KMT2ACA1CA2CA4HTT | |
| SCHEMBL2195774 | 0.90 | KMT2A (0.47) | KMT2ACA1CA2CA4HTT | |
| SCHEMBL2195766 | 0.90 | KMT2A (0.47) | KMT2ACA1CA2CA4HTT | |
| SCHEMBL2195770 | 0.90 | KMT2A (0.47) | KMT2ACA1CA2CA4HTT | |
| SCHEMBL2195800 | 0.84 | KMT2A (0.42) | KMT2ACA1CA2CA4TLR4 | |
| SCHEMBL19321816 | 0.83 | — | — | |
| SCHEMBL15515609 | 0.83 | — | — | |
| SCHEMBL19321813 | 0.83 | — | — | |
| SCHEMBL11372983 | 0.81 | KMT2A (0.53) | KMT2ACA1CA2CA4HTT | |
| SCHEMBL2864371 | 0.78 | KMT2A (0.52) | KMT2ACA1CA2CA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102736-A2 | PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES | QUEST INTERNATIONAL B.V. (NL) | 2001-05-30 | — | — | EP | disclosed |
| EP-0976714-A1 | Addition of ketones to alkenes | QUEST INTERNATIONAL B.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-2000001648-A2 | PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES | QUEST INTERNATIONAL B.V. (NL) | 2000-01-13 | — | — | WO | disclosed |