Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135459 | 0.90 | HDAC1 (0.65) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL5161699 | 0.78 | HDAC1 (0.56) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL10761716 | 0.78 | HDAC2 (0.73) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL8352548 | 0.77 | HDAC1 (0.66) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL8164536 | 0.77 | HDAC2 (0.71) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL1689083 | 0.76 | HDAC1 (0.71) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL4258366 | 0.76 | HDAC1 (0.75) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL2410081 | 0.76 | HDAC1 (0.78) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL751214 | 0.76 | HDAC2 (0.80) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL95051 | 0.75 | HDAC2 (0.73) | HDAC2HDAC8HDAC6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065117-A1 | INHIBITION OF HDAC2 TO PROMOTE MEMORY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-06-10 | — | — | WO | disclosed |