Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937566 | 0.85 | MAPT (0.54) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9776713 | 0.78 | MAPT (0.58) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30395442 | 0.75 | LRRK2 (0.65) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2060438 | 0.75 | LRRK2 (0.65) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22606149 | 0.74 | CDK5 (0.65) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27751334 | 0.74 | MAPT (0.56) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3106418 | 0.74 | MAPT (0.69) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10501815 | 0.73 | KHK (0.46) | SMN1; SMN2TSHRHSD17B10LMNAHTT | |
| SCHEMBL2843128 | 0.73 | ALK (0.58) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4922231 | 0.73 | EGFR (0.52) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |