Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965998 | 0.98 | PRSS1 (0.55) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL22117182 | 0.94 | PRSS1 (0.59) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL839678 | 0.92 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL43233 | 0.90 | PRSS1 (0.67) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL44568 | 0.90 | PRSS1 (0.62) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL6306550 | 0.88 | PRSS1 (0.51) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL25297232 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL20564639 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL1531270 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 | |
| SCHEMBL21879662 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627670-B | Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof | UNIV SHIJIAZHUANG | 2014-11-26 | — | — | CN | claimed |
| CN-105968192-A | Biopesticide artificial antigen synthesizing method | 周启新 | 2016-09-28 | — | — | CN | disclosed |
| CN-105968193-A | Biopesticide artificial antigen synthesizing method | 周启新 | 2016-09-28 | — | — | CN | disclosed |
| CN-104789027-B | Modified drift-sand and the polyurethane coating containing this modification drift-sand | 郝情情 | 2016-08-24 | — | — | CN | disclosed |
| CN-102627670-B | Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof | UNIV SHIJIAZHUANG | 2014-11-26 | — | — | CN | disclosed |
| CN-103889994-A | Universal and stereospecific synthesis of gamma-unsaturated amino acids by Wittig reaction | CENTRE NAT RECH SCIENT | 2014-06-25 | — | — | CN | disclosed |
| CN-102920969-A | Traditional Chinese medicine compound preparation for treating vasculitis, ischialgia and spondylitis, and preparation method thereof | ZHANG SHENGHUI | 2013-02-13 | — | — | CN | disclosed |
| CN-102627670-A | Aryl alkyl acid-cyclophosphamide derivative as well as preparation method and application thereof | UNIV SHIJIAZHUANG | 2012-08-08 | — | — | CN | disclosed |
| CN-102197503-A | Energy converter based on polyurethane solution | BAYER MATERIALSCIENCE AG | 2011-09-21 | — | — | CN | disclosed |
| WO-2011034212-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING A PATTERN USING THE SAME | FUJIFILM CORPORATION (JP) | 2011-03-24 | — | — | WO | disclosed |
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| CN-1209129-A | Antagonists of gonadotropin releasing hormone | MERCK & CO LTD (US) | 1999-02-24 | — | — | CN | disclosed |
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| CN-1190397-A | Heteroaromatic diphophines as chiral ligands | ITALFARMACO SUD SPA (IT) | 1998-08-12 | — | — | CN | disclosed |
| US-5055573-A | Reacting substituted azetidinone with glyoxalate ester, halogenating, reacting with phosphine, oxidizing, cyclizing, deprotecting | MERCK & CO., INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-4775669-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4543257-A | PENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1985-09-24 | — | — | US | disclosed |