SCHEMBL7943012

SCHEMBL7943012

Clc1ccc(Cl)c(C(Cl)(Cl)Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.65
CYP3A4 P08684 5/20 0.65
TDP1 Q9NUW8 4/20 0.65
MAPK1 P28482 1/20 0.65
TP53 P04637 3/20 0.50
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.35
CYP2A6 P11509 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AHR P35869 1/20 0.34
IDO1 P14902 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HTR2B P41595 1/20 0.33
PDE4D Q08499 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965839 1.00 TSHR (0.65) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL11865542 0.84 TSHR (0.52) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL11683376 0.81 TSHR (0.68) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL11862899 0.80 TSHR (0.48) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL1845000 0.79 TSHR (1.00) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL29402968 0.79 TSHR (1.00) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL18167274 0.77 CYP3A4 (0.56) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL11548525 0.77 TSHR (0.65) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL987352 0.77 IDO1 (0.50) TSHRCYP3A4TDP1MAPK1TP53
SCHEMBL29649700 0.77 IDO1 (0.50) TSHRCYP3A4TDP1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-1985594-A Preparing process of rotenone water emulsion NONGLE BIOLOG PRODUCT CO LTD (CN) 2007-06-27 CN claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP disclosed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO disclosed
CN-118221496-A Synthesis method of polysubstituted (trichloromethyl) benzene derivative 浙江工业大学 2024-06-21 CN disclosed
CN-118206441-A Preparation method of trifluoromethyl benzoic acid 黑龙江邦普生物科技有限公司 2024-06-18 CN disclosed
CN-111094224-A Improved process for preparing trifluoromethylbenzaldehydes and intermediates thereof SRF有限公司 2020-05-01 CN disclosed
CN-1985594-B Preparing process of rotenone water emulsion SHANGHAI NONGLE BIOLOG PRODUCT CO LTD 2010-08-18 CN disclosed
CN-1985594-A Preparing process of rotenone water emulsion NONGLE BIOLOG PRODUCT CO LTD (CN) 2007-06-27 CN disclosed
US-6201161-B1 Method of reducing benzaldehyde or benzotrihalide content in a mixture OCCIDENTAL CHEMICAL CORPORATION 2001-03-13 US disclosed
US-5273627-A Contacting the mixture with an inert gas at 100-200 C. to remove gaseous hydrogen chloride; distilling in the presence of amines and/or chorinated amines BAYER AKTIENGESELLSCHAFT (DE) 1993-12-28 US disclosed
US-5244965-A Polymer solution treatment process POLYSAR LIMITED (CA) 1993-09-14 US disclosed
EP-0372262-A1 Method for the destillative processing of mixtures containing side chain chlorinated alkylaromatics BAYER AG (DE) 1990-06-13 EP disclosed
EP-0325198-A1 Polymer solution treatment process POLYSAR LIMITED (CA) 1989-07-26 EP disclosed
US-4163753-A FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND Diaz Chemical Corporation (US) 1979-08-07 US disclosed