Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 1.00 |
| ▸ | TTR | P02766 | 4/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | IAPP | P10997 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358970 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL19359050 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL15009234 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL19358977 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL3240552 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL19359049 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| Hexylcaffeate SCHEMBL19358999 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL19358992 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL19358989 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 | |
| SCHEMBL16428905 | 1.00 | APP (1.00) | APPTTRDPP4IAPPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111296445-A | Laurella solanacearum targeted nano medicament and preparation method and application thereof | 江苏科技大学 | 2020-06-19 | — | — | CN | claimed |
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | claimed |
| EP-3713604-B1 | COMPOUND FOR USE IN THE INCREASING OF MENTAL CAPABILITY | LEIBNIZ INST FUER NEUROBIOLOGIE LIN STIFTUNG DES OEFFENTLICHEN RECHTS (DE) | 2023-06-07 | — | — | EP | disclosed |
| CN-111296445-B | Laurella solanacearum targeted nano medicament and preparation method and application thereof | 江苏科技大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-111296445-A | Laurella solanacearum targeted nano medicament and preparation method and application thereof | 江苏科技大学 | 2020-06-19 | — | — | CN | disclosed |
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20140127316-A1 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF | NEW YORK UNIVERSITY | 2014-05-08 | — | — | US | disclosed |
| WO-2013012477-A1 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2013-01-24 | — | — | WO | disclosed |
| US-6265344-B1 | WHICH IS SUITABLE FOR A FILM FOR A VIDEO PRINTER. | RICOH COMPANY, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6066311-A | ESTERIFICATION OF CHLOROGENIC ACID WITH AN ESTERIFYING ENZYME. CAFFEIC ACID AND ITS DERIVATIVES, PRODUCED BY THIS METHOD, MAY BE USED IN SUNSCREEN COMPOSITIONS, THE CAFFEIC ACID AND ITS DERIVATIVES ABSORBING BOTH UVA AND UVB LIGHT. | ZYLEPSIS LIMITED (GB) | 2000-05-23 | — | — | US | disclosed |
| US-5952263-A | PROTECTIVE LAYER FORMED OF A RESIN WITH MICROSCOPICALLY ROUGH SURFACE HORIZONTALLY CUT AT EQUALLY SPACED INTERVALS; HIGH TRANSPARENCY, IMAGE QUALITY WITHOUT WHITE STREAKS AND NONSTICKING TO THERMAL PRINTHEADS | RICOH COMPANY, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| US-5935899-A | PROTECTIVE LAYER COMPRISING SPHERICAL FILLER AND AN IRREGULAR SHAPED FILLER; NON-STICKING TO THERMAL HEAD, NO WHITE STRIPE, DECREASED HEAD DEFACEMENT; COMPUTERS, FACSIMILE MACHINES; LABEL PRINTERS | RICOH COMPANY, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5866507-A | BLEND OF BINDER AND COLORING AGENT | RICOH COMPANY, LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5792724-A | HIGH TRANSMITTANCE DENSITY, EXCELLENT REPRODUCIBILITY OF FINE DOT AND HALF TONE IMAGES; MIXTURE OF BINDER RESINS WITH DIFFERENT GLASS TRANSIFION TEMPERATURES | RICOH CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0764147-A1 | PRODUCTION AND USES OF CAFFEIC ACID AND DERIVATIVES THEREOF | ZYLEPSIS LIMITED (GB) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995033706-A1 | PRODUCTION AND USES OF CAFFEIC ACID AND DERIVATIVES THEREOF | ZYLEPSIS LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127316-A1 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF | EP300, HDAC1, HDAC8 | APP 1017/4885TTR 2988/4885DPP4 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.