SCHEMBL7944378

SCHEMBL7944378

CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 1.00
MAPT P10636 2/20 1.00
MEN1 O00255 2/20 1.00
CYP3A4 P08684 2/20 1.00
ALOX15 P16050 2/20 1.00
ALDH1A1 P00352 1/20 1.00
UGT1A1 P22309 1/20 1.00
SQLE Q14534 7/20 0.71
KDM4E B2RXH2 1/20 0.59
ICMT O60725 1/20 0.57
FNTA P49354 1/20 0.53
FNTB P49356 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Geranylgeraniol SCHEMBL127330 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Farnesol SCHEMBL17633996 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Geranylgeraniol SCHEMBL17557239 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Geranylgeraniol SCHEMBL16664300 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL4717874 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Geranylgeraniol SCHEMBL23814969 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Farnesol SCHEMBL6422271 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Solanesol SCHEMBL4762223 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Farnesol SCHEMBL7546574 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL16664315 1.00 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11407704-B2 Process of vitamin K2 derivatives preparation SIEC BADAWCZA LUKASIEWICZ-INSTYTUT CHEMII PRZEMYSLOWEJ IMIENIA PROFESORA IGNACEGO MOSCICKIEGO (PL) 2022-08-09 US disclosed
EP-2868658-B1 Method of preparation of stereospecific quinone derivatives MEHTA DILIP (US) 2018-05-02 EP disclosed
EP-2868658-B1 Method of preparation of stereospecific quinone derivatives MEHTA DILIP (US) 2018-05-02 EP disclosed
US-9828323-B2 Process for preparation of MK-7 type of vitamin K2 NATTOPHARMA R & D LTD. (CY) 2017-11-28 US disclosed
US-9828323-B2 Process for preparation of MK-7 type of vitamin K2 NATTOPHARMA R & D LTD. (CY) 2017-11-28 US disclosed
US-9464021-B2 Method of preparation of stereospecific quinone derivatives MEHTA DILIP S (IN) 2016-10-11 US disclosed
US-9464021-B2 Method of preparation of stereospecific quinone derivatives MEHTA DILIP S (IN) 2016-10-11 US disclosed
US-9464021-B2 Method of preparation of stereospecific quinone derivatives MEHTA DILIP S (IN) 2016-10-11 US disclosed
US-20150291498-A1 PROCESS FOR PREPARATION OF MK-7 TYPE OF VITAMIN K2 NATTOPHARMA R&D LTD (CY) 2015-10-15 US disclosed
US-20150291498-A1 PROCESS FOR PREPARATION OF MK-7 TYPE OF VITAMIN K2 NATTOPHARMA R&D LTD (CY) 2015-10-15 US disclosed
US-20080051451-A1 Autoimmune conditions and NADPH oxidase defects BIOVITRUM AB (SE) 2008-02-28 US disclosed
WO-2007104790-A1 AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS BIOVITRUM AB (PUBL) (SE) 2007-09-20 WO disclosed
US-6288128-B1 β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound EISAI CO., LTD. (JP) 2001-09-11 US disclosed
US-6111131-A SUCH AS 3,7,11,15,19,23,27,31-OCTAMETHYL-2,6,10,14,18,22,26,30-DOTRIACONTAOCTAEN-1 -OL; USEFUL AS PROPHYLACTIC DRUG FOR IMMUNODEFICIENCY DISEASES AND INFECTIOUS DISEASES EISAI CO., LTD. (JP) 2000-08-29 US disclosed
US-5658958-A β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals EISAI CO., LTD. (JP) 1997-08-19 US disclosed
EP-0304842-B1 Isoprenoid derivatives and anti-ulcer agents containing the same NISSHIN FLOUR MILLING CO (JP) 1994-11-30 EP disclosed
US-5280048-A Antiinfection agent EISAI CO., LTD. (JP) 1994-01-18 US disclosed
US-4906669-A Isoprenoid derivatives and anti-ulcer agents containing the same NISSHIN FLOUR MILLING CO., LTD. (JP) 1990-03-06 US disclosed
EP-0304842-A2 Isoprenoid derivatives and anti-ulcer agents containing the same NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-03-01 EP disclosed
US-4624966-A β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound EISAI CO., LTD. (JP) 1986-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291498-A1 PROCESS FOR PREPARATION OF MK-7 TYPE OF VITAMIN K2 SIRT7, PROC, F7 KMT2A 384/4885MAPT 4863/4885MEN1 38/4885
US-20080051451-A1 Autoimmune conditions and NADPH oxidase defects CYBB, NOX1, NOX5 KMT2A 3330/4885MAPT 3853/4885MEN1 3279/4885
US-11407704-B2 Process of vitamin K2 derivatives preparation PROC, VKORC1, VKORC1L1 KMT2A 1147/4885MAPT 4639/4885MEN1 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.