Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 11/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951817 | 1.00 | GRIA2 (0.53) | GRIA2KCNH2GRIA4 | |
| SCHEMBL7945075 | 0.91 | GRIA2 (0.53) | GRIA2KCNH2GRIA4 | |
| SCHEMBL7948234 | 0.91 | GRIA2 (0.53) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2187568 | 0.88 | GRIA2 (0.60) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2187204 | 0.88 | GRIA2 (0.60) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2187560 | 0.88 | GRIA2 (0.60) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2187196 | 0.88 | GRIA2 (0.60) | GRIA2KCNH2GRIA4 | |
| SCHEMBL7950216 | 0.87 | GRIA2 (0.54) | GRIA2KCNH2GRIA4 | |
| SCHEMBL7946551 | 0.87 | GRIA2 (0.54) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2188063 | 0.85 | GRIA2 (0.59) | GRIA2KCNH2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038167-A1 | OXOPIPERIDINYL AND PYRANYL SULFONAMIDES AS AMPA POTENTIATORS | PFIZER INC. (US) | 2010-04-08 | — | — | WO | disclosed |