Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941377 | 0.96 | GSR (0.48) | GSRSCN2AHSPA5CYP3A4CYP2C9 | |
| SCHEMBL7941230 | 0.92 | GSR (0.59) | GSRSCN2AHSPA5CYP3A4CYP2C9 | |
| SCHEMBL7933726 | 0.80 | HSPA5 (0.57) | GSRSCN2AHSPA5CYP3A4CYP2C9 | |
| SCHEMBL7943209 | 0.80 | GSR (0.51) | GSRSCN2AHSPA5CYP3A4CYP2C9 | |
| SCHEMBL28492613 | 0.77 | HSPA5 (0.43) | GSRHSPA5CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7943330 | 0.76 | GSR (0.81) | GSRSCN2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7933606 | 0.76 | HSPA5 (0.55) | GSRSCN2AHSPA5CYP3A4CYP2C9 | |
| SCHEMBL7940416 | 0.76 | GSR (0.50) | GSRSCN2AHSPA5CYP3A4CYP2C9 | |
| SCHEMBL10708543 | 0.75 | HSPA5 (0.56) | HSPA5CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7940078 | 0.75 | HSPA5 (0.36) | GSRSCN2AHSPA5CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |