⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932940 | 0.62 | — | — | |
| SCHEMBL3130973 | 0.62 | — | — | |
| SCHEMBL5821772 | 0.62 | — | — | |
| SCHEMBL620794 | 0.62 | — | — | |
| SCHEMBL4802200 | 0.57 | — | — | |
| SCHEMBL4984882 | 0.57 | — | — | |
| SCHEMBL4724714 | 0.57 | — | — | |
| SCHEMBL4933560 | 0.57 | — | — | |
| SCHEMBL8209871 | 0.47 | — | — | |
| SCHEMBL21947377 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689339-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2020-06-23 | — | — | US | claimed |
| US-20180362461-A1 | NOVEL PYRROLIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2018-12-20 | — | — | US | claimed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-108699044-B | Novel pyrrolidine derivatives | 豪夫迈·罗氏有限公司 | 2022-03-04 | — | — | CN | disclosed |
| US-10689339-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| EP-3131896-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2019-01-30 | — | — | EP | disclosed |
| EP-3419970-A1 | NOVEL PYRROLIDINE DERIVATIVES | H. Hoffnabb-La Roche Ag (CH) | 2019-01-02 | — | — | EP | disclosed |
| US-20180362461-A1 | NOVEL PYRROLIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2018-12-20 | — | — | US | disclosed |
| US-9969724-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| WO-2015160634-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-2616458-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034960-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-5019490-A | Chlorotrifluoroethylene Polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |