Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100963 | 1.00 | TSHR (0.61) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL6821605 | 1.00 | TSHR (0.61) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL10587561 | 1.00 | TSHR (0.61) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL9736474 | 0.98 | TSHR (0.64) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL8187268 | 0.93 | TSHR (0.71) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL11313358 | 0.88 | TSHR (0.70) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL31578944 | 0.88 | TSHR (0.70) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL31578856 | 0.88 | TSHR (0.70) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL31579008 | 0.88 | TSHR (0.70) | TSHRLMNAALDH1A1L3MBTL1EPHX2 | |
| Hydrochloric Acid SCHEMBL9033471 | 0.86 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102736-A2 | PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES | QUEST INTERNATIONAL B.V. (NL) | 2001-05-30 | — | — | EP | disclosed |
| EP-0976714-A1 | Addition of ketones to alkenes | QUEST INTERNATIONAL B.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-2000001648-A2 | PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES | QUEST INTERNATIONAL B.V. (NL) | 2000-01-13 | — | — | WO | disclosed |