⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111181 | 1.00 | — | — | |
| SCHEMBL2499904 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL25212727 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL28590964 | 0.97 | — | — | |
| SCHEMBL10686177 | 0.94 | TSHR (0.55) | — | |
| Dimethylamine SCHEMBL7886857 | 0.91 | TSHR (0.52) | — | |
| Methoxymethane SCHEMBL9576631 | 0.91 | TSHR (0.52) | — | |
| 1,4-Butanediol SCHEMBL28034679 | 0.91 | TSHR (0.52) | — | |
| SCHEMBL6706837 | 0.90 | TSHR (0.50) | — | |
| SCHEMBL2380118 | 0.88 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4703476-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE ALKYL DIOLS AND DERIVATIVES THEREOF | Technische Universität Graz (AT) | 2026-03-04 | — | — | EP | disclosed |
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-3303326-B1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2020-12-16 | — | — | EP | disclosed |
| CN-107531722-B | Heterocyclic estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2020-07-17 | — | — | CN | disclosed |
| US-10053451-B2 | Heterocyclic estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2018-08-21 | — | — | US | disclosed |
| EP-3303326-A1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | H. Hoffnabb-La Roche Ag (CH) | 2018-04-11 | — | — | EP | disclosed |
| US-9868704-B2 | Estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-9868704-B2 | Estrogen receptor modulators and uses thereof | GENENTECH, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| EP-3205648-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-3205648-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20020110651-A1 | Optical laminate | NIPPON MITSUBISHI OIL CORPORATION | 2002-08-15 | — | — | US | disclosed |
| US-20020075431-A1 | Reflection-type liquid crystal display device | NIPPON MITSUBISHI OIL CORPORATION | 2002-06-20 | — | — | US | disclosed |
| EP-1211549-A1 | REFLECTION LIQUID CRYSTAL DISPLAY DEVICE | Nippon Mitsubishi Oil Corporation (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-1203968-A1 | OPTICAL LAMINATE | Nippon Mitsubishi Oil Corporation (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-5456867-A | Viewing angle compensator for liquid crystal display | NIPPON OIL COMPANY, LIMITED (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0529813-A2 | Compensator for a liquid crystal display | Nippon Oil Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4902818-A | Process for the manufacture of optically active compounds | HOFFMANN-LA ROCHE INC. (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0104376-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINES AND ENAMINES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-05-06 | — | — | EP | disclosed |
| US-4578462-A | Process for the manufacture of optically active compounds | HOFFMANN-LA ROCHE INC. (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0104376-A2 | Process for the preparation of optically active amines and enamines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-04-04 | — | — | EP | disclosed |