Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814300 | 0.80 | DHODH (0.56) | DHODHNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7938910 | 0.78 | KMT2A (0.47) | NPC1RAB9ASMN1; SMN2HPGDGRM4 | |
| SCHEMBL7948458 | 0.77 | KMT2A (0.63) | NPC1RAB9ASMN1; SMN2HPGDGRM4 | |
| SCHEMBL6814307 | 0.75 | DHODH (0.50) | DHODHNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7947411 | 0.75 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL2119568 | 0.70 | HPGD (0.74) | DHODHNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL19501494 | 0.70 | HPGD (0.86) | NPC1RAB9ASMN1; SMN2HPGDTYK2 | |
| SCHEMBL4255638 | 0.70 | DHODH (0.73) | DHODHNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL19799127 | 0.70 | DHODH (0.68) | DHODHNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL6814905 | 0.68 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |