SCHEMBL7945971

SCHEMBL7945971

CC[Si](Cl)(C1=CC=CC1)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8197553 0.77
SCHEMBL8182591 0.77
SCHEMBL4652591 0.76 ESR1 (0.30)
SCHEMBL7622836 0.76
SCHEMBL9143969 0.74
SCHEMBL9143873 0.74
SCHEMBL7049680 0.72
SCHEMBL8370594 0.72
SCHEMBL4652414 0.72
SCHEMBL6673852 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6228790-B1 CATALYSTS FOR PREPARING OLEFIN POLYMERS WITH BIMODAL MOLECULAR WEIGHT DISTRIBUTION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-05-08 US disclosed
JP-2000169492-A BINUCLEAR METALLOCENE CATALYST FOR PRODUCING OLEFIN POLYMER OF HIGH MOLECULAR WEIGHT IND TECHNOL RES INST 2000-06-20 JP disclosed
US-6072067-A Cyclopentadiene compound substituted with a hetero atom-containing group DSM N.V. (NL) 2000-06-06 US disclosed
EP-0985676-A1 Dinuclear metallocene catalyst for preparing high molecular weight olefin polymer INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2000-03-15 EP disclosed
US-5986029-A POLYMERIZATION CATALYSTS FOR OLEFINS USING TRANSITION METAL COMPLEXES AND COCATALYST DSM N.V. (NL) 1999-11-16 US disclosed