Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244570 | 0.83 | NPSR1 (0.46) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL17922691 | 0.82 | ADORA2A (0.48) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL3980110 | 0.82 | GRM2 (0.46) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL112919 | 0.80 | NPSR1 (0.49) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL31098475 | 0.80 | KDM4A (0.43) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL15436036 | 0.79 | CYP1A2 (0.56) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL26616825 | 0.78 | NPSR1 (0.49) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL28520175 | 0.77 | ADORA2A (0.47) | KDM4ANPSR1GLSNAMPTPOLB | |
| SCHEMBL16551970 | 0.77 | KDM4A (0.41) | KDM4ANPSR1GLSNAMPTL3MBTL1 | |
| SCHEMBL29510880 | 0.77 | NPSR1 (0.47) | KDM4ANPSR1GLSNAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009334-A1 | METHOD FOR PREPARING LARGAZOLE ANALOGS AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-01-21 | — | — | WO | disclosed |