Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151288 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6641224 | 0.80 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8347975 | 0.80 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7951249 | 0.80 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6777867 | 0.79 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL6770437 | 0.79 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL7346002 | 0.78 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6968888 | 0.78 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL8347194 | 0.78 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6770736 | 0.77 | EDNRA (0.71) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939446-A | HYPOTENSIVE AGENTS FROM ISOXAZOLESULFONAMIDES | BRISTOL-MYERS SQUIBB CO. (US) | 1999-08-17 | — | — | US | claimed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |
| US-5939446-A | HYPOTENSIVE AGENTS FROM ISOXAZOLESULFONAMIDES | BRISTOL-MYERS SQUIBB CO. (US) | 1999-08-17 | — | — | US | disclosed |