Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757854 | 0.94 | MAPT (0.59) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL17309872 | 0.91 | MAPT (0.68) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL1303931 | 0.91 | MAPT (0.68) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL6367781 | 0.90 | KLK7 (0.52) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL6363676 | 0.90 | KLK7 (0.52) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL10873871 | 0.88 | KLK7 (0.67) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL8955505 | 0.88 | KLK7 (0.64) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL19732512 | 0.87 | CCR6 (0.59) | KLK7KLK5MAPTFOLH1PAX8 | |
| SCHEMBL2329143 | 0.86 | KLK7 (0.67) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL2329138 | 0.86 | KLK7 (0.67) | KLK7KLK5MAPTITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258931-B1 | SYNTHESIZING DEOXYHYPUSINE DERIVATIVE BY USING ESTER OF DIPROTECTED LYSINE, DEBLOCKING ONE NITROGEN, CONDENSING WITH 3-CYANOPROPANAL, REDUCING TO A TRIAMINE, PROTECTING FREE AMINO GROUPS, DEBLOCKING AGAIN, AND ACYLATING THE FREE AMINO GROUP | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2001-07-10 | — | — | US | disclosed |