Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952755 | 0.82 | HRH3 (0.49) | HRH3HRH1KDM2BHDAC6OPRM1 | |
| SCHEMBL1788776 | 0.79 | HRH3 (0.54) | HRH3KDM2BHDAC6 | |
| SCHEMBL1789796 | 0.79 | HRH3 (0.54) | HRH3KDM2BHDAC6 | |
| SCHEMBL1787705 | 0.79 | HRH3 (0.61) | HRH3HRH1KDM2BHDAC6 | |
| SCHEMBL7948137 | 0.79 | HRH3 (0.48) | HRH3HRH1KDM2BHDAC6 | |
| SCHEMBL1789719 | 0.78 | HRH3 (0.53) | HRH3KDM2BHDAC6 | |
| SCHEMBL2822496 | 0.77 | HRH3 (0.56) | HRH3HRH1KDM2BHDAC6 | |
| SCHEMBL7939650 | 0.77 | HRH3 (0.46) | HRH3HRH1KDM2BOPRM1OPRK1 | |
| SCHEMBL1788539 | 0.76 | HRH3 (0.51) | HRH3KDM2BHDAC6 | |
| SCHEMBL1789861 | 0.76 | HRH3 (0.48) | HRH3HRH1KDM2BHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007382-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED. (JP) | 2010-01-21 | — | — | WO | disclosed |