Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361902 | 0.87 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2HRH3SOS1 | |
| SCHEMBL3362794 | 0.85 | SLC6A4 (0.79) | SLC6A4SLC6A3SLC6A2HRH3SOS1 | |
| SCHEMBL3361717 | 0.85 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2HRH3SOS1 | |
| SCHEMBL3360984 | 0.84 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2HRH3SOS1 | |
| SCHEMBL3360981 | 0.84 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2HRH3SOS1 | |
| SCHEMBL7737285 | 0.84 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2HRH3SOS1 | |
| SCHEMBL6953667 | 0.83 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2HRH3HTR2A | |
| SCHEMBL930692 | 0.83 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2SOS1 | |
| SCHEMBL30682154 | 0.83 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2SOS1 | |
| SCHEMBL6955114 | 0.82 | SLC6A4 (0.78) | SLC6A4SLC6A3SLC6A2HRH3SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |
| WO-2010021681-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-02-25 | — | — | WO | disclosed |